The influenza A virus genome consists of 8 negative sense single strand RNA molecules.

The virus encodes 11 proteins.

• PA
• PB1and PB1-F2 (from an overlapping ORF, skipping 1st MET)
• PB2
• hemagglutinin (HA)
• neuraminidase (NA)
• nucleoprotein (NP)
• M1 and M2 from splicing of segment 7 mRNA
• NS1 and NS2(NEP) from splicing of segment 8 mRNA

Specific Influenza Functions (courtesy of Dr. Vincent Racaniello's blog)

• Influenza virus attachment to cells: role of different sialic acids
• The error-prone ways of RNA synthesis
• Release of influenza viral RNAs into cells
• Influenza viral RNA synthesis

Influenza NA

Mapping the sequence mutations of the 2009 H1N1 influenza A virus neuraminidase relative to drug and antibody binding sites  Biology-Direct 2009