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October 3-6, 2009
Leave on overnight ferry from Marseille to Ajaccio on the evening of Oct 2nd at 8 pm. (map and directions to go the ferry terminal)
On board you are invited to attend the welcome cocktail reception on the upstairs level of the bar “Le Galaxie” at 7.30 pm. The reception is being sponsored by Arrow Therapeutics/Astra Zeneca. Dinner will follow at 8:30 pm. We will arrive in Corsica at 7 am Oct 3rd.
All sessions in Ajaccio Oct 3-6
Saturday, October 3
Focus: The UNITAID funding model is evolving. This innovative funding model will be presented by Dr. Philippe Douste-Blazy, UN Under-Secretary for Innovative Financing. The research and drug & diagnostic development communities need to develop an « innovative spending » model that meets the expectations of these emerging innovative funding mechanisms. ICAV will present a « straw-man » proposal for discussion and elaboration.
| Chair: Michel Chrétien (OHRI, Canada) | |
| Speakers: | |
| 10:00-10:45am | Philippe Douste-Blazy (UNITAID, France) |
| 10:45-11:30am | Jeremy Carver (ICAV, Canada) "Suggestions for Innovative Spending" |
| 11:30-12:00pm | Panelists and Discussion: R.S. Paranjape (NARI, India) Oyekanmi Nashiru (ICAV, Nigeria) Sunday Omilabu (University of Lagos, Lagos) |
| 12:00-1:00pm | Lunch |
Afternoon
Session 2: HIV – Present and Future Challenges
Focus: What’s next in the HIV field regarding novel therapeutic avenues, vaccine design, community-based awareness, and innovative funding and incentives in a global context where public attention is competed by the worldwide financial crisis as well as novel pandemic threats?
| Chair: Bruno Canard | |
| Speakers: | |
| 01:00-01:45pm | Anne-Sophie Beignon (Pasteur Institute, France) “AIDS vaccine: where are we now?” |
| 01:45-02:30pm | Jan ter Muelen (Merck, USA) “Current challenges to the development of HIV vaccines and antivirals” |
| 02:30-03:00pm | Jörg Hofmann (Charité Campus Benjamin Franklin, Germany) “Long-term control of HIV by allogeneic CCR5-Δ32/Δ32 stem cell transplantation” |
| 03:00-03:30pm | Coffee Break |
| 03:30-04:00pm | Evelyne Jacqz-Aigrain (hospital Robert Debre, France) “How to increase availability of drugs for children : scientific and regulatory aspects” |
| 04:00-04:30pm | R.S. Paranjape (NARI, India) “Virology of Indian HIV epidemic and initiatives for anti-HIV drug development” |
| 04:30-05:00pm | Bruno Spire (INSERM, France) “Perceptions and behaviors of people living with HIV/AIDS : the interest of a multidisciplinary approach” |
| 05:00-05:30pm | Panelists: Anna Vyakarnam (King's College, UK) James Brandful (Noguchi Memorial Inst. of Medical Research, Ghana) Jonathan Stoye (Mill Hill, UK) Dana Wolf (Hadassah University Hospital, Israel) |
| 05:30-06:00pm | Discussion |
| 07:00-09:00pm | Cocktails and Dinner |
Sunday, October 4
Session 3: Dengue – An integrated model for arthropod-borne viral disease control Focus: Dengue is a robustly emerging disease transmitted by mosquitoes of the Aedes species in tropical and subtropical areas of the world. The global disease burden and control challenge has made of Dengue a model for other arthropod-borne diseases in terms of science, prevention, vector control, community-based measures, societal and economic impact. The goal of this session is to integrate all aspects related to dengue research in order to organize and impact the nascent field of emerging virus control strategies.
| Chair: Olaf Horstick (WHO, Switzerland) | |
| Speakers: | |
| 08:30-09:15am | Eva Harris (UC-Berkley, USA) “Dengue: From the bench to the field and back” |
| 09:15-10:00am | Xavier de Lamballerie (Universite Aix Marseille 2, France) “Arbovirus evolution and quasispecies: arguments for implementing antiviral treatments” |
| 10:00-10:30am | Coffee Break |
| 10:30-11:00am | Jerome Deval (Roche, Palo Alto, USA) “Inhibiting the polymerase of Dengue Virus : a Company perspective” |
| 11:00-11:30am | Julien Lescar (Nanyang Technological University, Singapore) “Structural views of the NS3 and NS5 proteins from flaviviruses” |
| 11:30-12:00pm | Robert S. Fuller (USA) “A novel family of pharmacologically-validated, non-competitive inhibitors of furin as potential broad spectrum anti-virals and anti-microbials” |
| 12:00-12:30pm | Panelists: Bruno Canard (CNRS, France) Cecilia Dayaraj (NIV, India) Subhash Vasudevan (Duke-NUS Graduate Medical School, USA) Paul Young (University of Queensland, Australia) Wendy Hill (ICAV, Canada) |
| 12:30-01:00pm | Discussion |
| 01:00-02:00pm | Lunch |
Formal Poster Presentation Session
| 02:00-05:00pm | Poster Session |
| 02:30-03:30pm | MOU Signing (by invitation only) |
| 03:30-04:30pm | International Steering Committee Meeting (by invitation only) |
| 07:00-09:00pm | Cocktails and Dinner |
Monday, October 5
Morning
Session 4 & 5: Emerging Viruses
Focus: Emerging viruses impose a large number of totally novel constraints on society. Not only is scientific knowledge lacking regarding rapid implementation of control measures (eg. antivirals, vaccines), but challenges associated with vector control, community reaction and education, as well as funding schemes to develop efficient protective measures are totally undeveloped.
The current preparedness and response plans developed by public health agencies have not involved or engaged classical stakeholders, such as companies and academics, in a landscape where most response schemes (eg. classical grant-funded research, massive and rapid diagnostics, clinical trials, patient care…) are not suitable to face a crisis situation and need significant input from these sectors. This session will work on the identification and bridging of the numerous gaps in this rapidly evolving field.
The rapid emergence and spread of H1N1 with gene segments from swine, avian and human origin demonstrates the need for continued surveillance of all known reservoirs for influenza and the refinement of predictive methods for human-to-human transmission and virulence. Session 4 will focus on the global public health responses to the H1N1 pandemic and how they could be improved.
| Chair: Nabil Seidah (IRCM, Canada) | |
| Speakers: | |
| 08:30-09:15am | Ernest Gould (Oxford University, Oxford) “Emerging Viruses: Humans are man's worst enemy!” |
| 09:15-10:00am | Pilar Najarro (Arrow, UK ) “Industry’s challenges in antiviral drug discovery: a not-so-small company point of view” |
| 10:00-10:30am | Coffee Break |
| 10:30-11:00am | Noël Tordo (Institut Pasteur, France) “Antiviral strategies against negative strand RNA viruses” |
| 11:00-11:30am | Panelists: Rolf Hilgenfeld (University of Lübeck, Germany) Guenter Kraus (Tibotec, Belgium) Brahm Srivastava (CDRI, India) |
| 11:30-12:00pm | Discussion |
| 12:00-01:30pm | Lunch |
Afternoon
Focus on significant candidates
Focus : The rapid emergence and spread of H1N1 with gene segments from swine, avian and human origin demonstrates the need for continued surveillance of all known reservoirs for influenza and the refinement of predictive methods for human-to-human transmission and virulence. This session will focus on the global public health responses to the outbreak in Mexico how they could be improved. Updates on the threat from H5N1 will also be presented.
| Chair: Ernest Gould (University of Oxford, UK) | |
| Speakers: | |
| 01:30-02:15pm | Angela McLean (Oxford, UK) “Modeling Pandemics” |
| 02:15-03:00pm | Guy Boivin (Québec City University Hospital Center, Canada) “Influenza resistance to neuraminidase inhibitors” |
| 03:00-03:30pm | Coffee Break |
| 03:30-04:00pm | Bruno Canard (Laboratoire AFMB, France) “Broad spectrum preparedness against emerging viruses: Achievements of the VIZIER project. What's next?” |
| 04:00-04:30pm | Ernest Gould (University of Oxford, UK) “EVA - European Virus Archive” |
| 04:30-05:00pm | Panelists: Johan Neyts (University of Leuven, Belgium) Dale Cumming (ICAV, Canada) Junli Liu (China CDC/IST, China) Dana Wolf (Hadassah University Hospital, Israel) Yossef Av-Gay (University of British Columbia, Canada) Eleanor Fish (UHN, Canada) |
| 05:00-06:00pm | Discussion |
| 07:00-09:00pm | Cocktails and Gala Dinner – Pierre Jeanniot (FAV, Canada) |
| 09:00pm | Closing Comments - Michel Chrétien (OHRI, Canada) |
Session 6: "Late Breaking News"
| Chair: TBA | |
| 09:00-12:00pm | Speakers: |
Back to Marseille at the end of the day.
